In 2000, she graduated as an "Actress" and "Theatre Director" from the A.I.T. (International Academy of Theatre) in Rome (a course lasting 3 years).
She continued with the study of Ancient Comedy, Poetic Humor, and Clown techniques with Eric de Bont (ESP). In 2004, she specialized in Commedia dell'Arte with Antonio Fava (technical use of masks, study of "lazzi", roles, and interactions among the Commedia masks, study of Canovacci), one of the most important masters of Commedia dell'Arte in the world.
She continued her training with composition workshops for dance-theatre with Daniel Lepkov in Orvieto (IT); on theatrical techniques "Mystery and Smaller Pieces" held by the Living Theatre in Poznan (Poland).

Since 2002, she has been teaching movement techniques, Commedia dell'Arte masks, Allegorical and Modern Buffoon, interpretation and directing techniques in the professional courses of the International Academy of Theatre in Rome (IT) / Degree course recognized by MUIR.
Since 2005, she has been leading theatre workshops for children, teachers, and professionals in various schools, in both national and international contexts.

Her artistic research starts from the “concept” developed in the L.E.M. (Movement Study Workshop) by Architect Krikor Belekian and Educator Jacques Lecoq. This vision led her to study and develop an interaction between the performative body and the moving scenery, where the performer's body is linked to the imaginative power of the machine.
In 2005, she founded ONDADURTO TEATRO, a theatre company based in Rome. Led by Margò Paciotti and Lorenzo Pasquali, the company has developed thanks to the joint work of those who have been involved in projects and activities over the years. The research and creative work carried out by ONDADURTO TEATRO focuses on Physical Theatre, Nouveau Cirque, and the interaction between the performative body and the moving scenery.
The different expressive techniques used by the company help to create a strong visual language that allows interaction with people of any age, ethnicity, and culture and to reach an international audience. Performances and shows combine the action of the performers with the use of Large Moving Objects, Machinery, Fireworks, Water Effects, Video Projections, and Music.
ONDADURTO TEATRO's productions have toured in Italy and other European countries (such as DE / ES / FR / DK / LU / PL / AT / HU / CY / RO / ES-CN / IE) and traveled to other continents, including countries such as: Chile / Mexico / South Korea / Russia / United States. The company has also been involved in cultural exchange projects in Thailand/India/Cuba.
Margò has been responsible for the creation and direction of every show produced by the Company over the years.
More information at https://ondadurtoteatro.it

She co-directed several multidisciplinary performing arts festivals:
- INEUROFF Festival, for 9 editions in Rome at the monumental EUR site. The festival's focus was transforming a monumental site into an ideal stage. The key to the festival were multidisciplinary projects that mixed "site-specific", theatre, classical arias, docu-films, large-scale shows, dance, and live concerts. The festival was a Partner of the "River Cities" Project, a European platform for the development and promotion of cultural projects in urban spaces, funded by the European Cultural Foundation.
- INBORGO Festival, for 4 editions, aimed at creating interactions between performing arts, public and urban spaces.
- CUNTI E RACCONTI Festival for 5 editions, a festival born in the rural areas of Borgo Velino and Antrodoco, two small towns in the mountains near the city of Rome.
- From 2006 to 2015, she was active in Roma Communities using theatre and the arts as means to create connections and exchanges between cultures.

- In 2015-2017 and 2018-2020, she served as the artistic director of the International Project - CONTACT ZONES focused on Theatre and Arts in public spaces, co-funded by the EU – Creative Europe Programme (COOP1 SMALL SCALE) for 2 editions and awarded as a Success Story.
- For the DONIZETTI OPERA Festival, she directed the opera "PIETRO THE GREAT - Kzar of all Russias" and was also in charge of costumes, scenography, and machinery for the 2019 season.

Since 2020, she has been the general director of DRAG ME UP – Queer Art Festival, a new format on the culture and performing arts of LGBTQIA+, funded by the Municipality of Rome and the Lazio Region. The Festival is an artistic platform that addresses gender issues through the lens of Drag "sub-culture". Designed as an international network for contemporary arts and LGBTQIA+ activism, it is a true showcase representing all gender expressions, highlighting the characteristics of the performers in a combination of ironic comedy and socio-cultural activism. From 2023, within the ESTATE ROMANA – Municipality of Rome schedule, the festival also opens to a summer section called QUEER SUMMER FESTIVAL, with a more specific focus on new contaminations and interconnections of Queer art.

Between 2021 and 2023, she curated (in collaboration with PROTAGON e.V. and DOREA INSITUTE) the European project RECONNECT supported by the ERASMUS+ "Creative" program aimed at promoting an international dialogue on gender equality and non-discrimination for the LGBTQIA+ Community with an intersectional approach.

In 2022, she founded the ARTS FOR GENDER REVOLUTION Platform, a network among EU and USA partners, aimed at creating connections between artists, creative industry professionals, and institutions, to promote events tied to a more inclusive society for the LGBTQIA+ communities.

Since 2021, she has been co-curator of R/Esistenza Street Art Gallery, a Street Art and Graffiti project realized by some of the most well-known Italian artists in rural and peripheral areas, with the goal of bringing art out of the major cities.

She co-directs ARIA / Antrodoco International Artist Residency, a project of Artistic Residences and Contemporary Performances that hosts new artistic productions and organizes workshops for young artists and professionals in the territory of Antrodoco in the Lazio Region (IT). The project is funded by the European Union/Next Generation EU, MiC (Italian Ministry of Cultural Heritage) and the Municipality of Antrodoco.

Since 2022, she has directed performances of international companies and artists such as KARMA B (Drag Queen duo - Italy), ANTAGON theaterAKTion (performing arts company - Germany) LOST IN TRANSLATION (contemporary circus company - United Kingdom) and has created 2 shows in which she is also an actress on stage.